If you're looking to improve skin texture, acne scars, fine lines, and overall skin quality, microneedling is one of the most effective treatments available. But today, many patients are enhancing their results by combining microneedling with regenerative therapies such as PRF or PDGF.
At Bare Skin, we believe healthy skin is the foundation of beautiful results. Combining microneedling with advanced growth factor therapies can help accelerate healing, support collagen production, and improve overall treatment outcomes.
Here's what you should know about microneedling with PRF and PDGF.
What Is Microneedling?
Microneedling is a minimally invasive treatment that creates controlled micro-injuries in the skin using tiny sterile needles.
These microchannels stimulate your body's natural healing response, increasing collagen and elastin production while improving overall skin quality.
Microneedling is commonly used to improve:
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Acne scars
Fine lines and wrinkles
Enlarged pores
Uneven skin texture
Mild skin laxity
Sun damage
Overall skin tone and radiance
While microneedling alone produces excellent results, pairing it with regenerative therapies can further
enhance the skin's healing and rejuvenation process.
What Is PRF?
PRF (Platelet-Rich Fibrin) is a regenerative treatment derived from your own blood.
After a small blood draw, the sample is processed to concentrate platelets, white blood cells, fibrin, and growth factors. These components help support tissue repair and stimulate collagen production.
Because PRF comes directly from your body, it is often considered a natural approach to skin rejuvenation.
When combined with microneedling, PRF can be applied topically through the microchannels created during treatment, allowing growth factors to penetrate more effectively.
Benefits of Microneedling with PRF
Microneedling with PRF may help:
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Stimulate collagen production
Improve acne scars
Support skin healing
Enhance overall skin quality
Improve skin texture and tone
Reduce the appearance of fine lines
Promote a healthy, radiant complexion
Many patients choose PRF because it utilizes their body's own natural regenerative properties.
What Is PDGF?
PDGF (Platelet-Derived Growth Factor) is a highly concentrated growth factor therapy designed to support tissue repair and skin rejuvenation.
Unlike PRF, which is derived from a patient's own blood, PDGF delivers a concentrated source of growth factors specifically selected for their ability to support healing and collagen production.
When paired with microneedling, PDGF can help optimize the skin's regenerative response following treatment.
Benefits of Microneedling with PDGF
Microneedling with PDGF may help:
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Accelerate post-treatment recovery
Support collagen and elastin production
Improve skin texture and tone
Enhance overall skin rejuvenation
Improve the appearance of fine lines
Support healthier, more resilient skin
Maximize the benefits of microneedling
Many patients appreciate PDGF because it provides a highly targeted regenerative approach to skin rejuvenation.
PRF vs PDGF: What's the Difference?
Both treatments are designed to enhance healing and improve microneedling results, but they work slightly differently.
PRF
PRF is:
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Derived from your own blood
Rich in platelets and growth factors
Completely autologous
Popular among patients seeking a natural treatment approach
PDGF
PDGF is:
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A concentrated growth factor treatment
Designed to optimize cellular repair
Focused on enhancing recovery and collagen stimulation
An excellent option for patients seeking advanced regenerative support
Neither option is universally better than the other. The right choice depends on your skin concerns, treatment goals, and personal preferences.
Which Conditions Respond Best?
Both PRF and PDGF can be beneficial for:
Acne Scarring
Collagen stimulation helps improve skin texture and soften the appearance of acne scars over time.
Fine Lines and Wrinkles
Improved collagen production can help create smoother, firmer-looking skin.
Uneven Skin Texture
Microneedling combined with regenerative therapies can improve overall skin smoothness and quality.
Dull or Aging Skin
Patients often notice brighter, healthier-looking skin and improved radiance after a series of treatments.
How Many Treatments Will I Need?
While many patients notice improvement after a single treatment, the best results typically occur with a
series of treatments.
Most treatment plans include:
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3–6 treatments
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Spaced approximately 4–6 weeks apart
The exact number will depend on your skin concerns and goals.
What Is Recovery Like?
Recovery is generally minimal.
Most patients experience:
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Redness for 24–72 hours
Mild sensitivity
Temporary dryness or roughness
The skin typically begins looking brighter and healthier within the first week, with ongoing collagen remodeling occurring for months after treatment.
Why We Love Combining Regenerative Therapies with Microneedling
Microneedling already stimulates your body's natural healing response. Adding PRF or PDGF can further support that process by providing growth factors that encourage collagen production and tissue repair.
For patients focused on long-term skin health, texture, and quality, these combinations can be a powerful addition to a comprehensive skincare plan.
The Bottom Line
Microneedling with PRF and microneedling with PDGF are excellent options for patients looking to improve skin quality, stimulate collagen production, and support long-term skin rejuvenation. Both treatments enhance the benefits of traditional microneedling while helping the skin heal and regenerate more efficiently.
At Bare Skin, we customize every treatment plan based on your unique skin concerns and goals. During your consultation, we'll help determine whether PRF, PDGF, or another regenerative approach is the best fit for your skin.
Frequently Asked Questions
Is PRF better than PDGF?
Neither treatment is universally better. PRF uses your body's own growth factors, while PDGF provides concentrated growth factor support. The best choice depends on your goals and preferences.
Does microneedling with PRF hurt?
Most patients tolerate treatment very well. Topical numbing cream is typically used to maximize comfort.
How long does it take to see results?
Many patients notice brighter skin within days, while collagen production and continued improvement develop over several weeks and months.
Can microneedling with PRF or PDGF help acne scars?
Yes. Both treatments are commonly used to improve skin texture and soften the appearance of acne scarring.
How often should I get microneedling with PRF or PDGF?
Most patients benefit from a series of treatments spaced approximately 4–6 weeks apart, followed by maintenance treatments as recommended.
